Nieuws 2018-01-08T13:15:02+00:00


Longevity mainly ascribed to an extremely long-lived mother

For many years, scientists in Leiden have been monitoring 421 exceptional families with several members who have lived way beyond the age of 90. A new analysis of these extremely long-lived persons, their siblings, and parents now shows that longevity in these families is passed on mainly through the mother. The researchers present their results in the scientific journal The Journal of Gerontology: Biological Sciences. (press release LUMC) ‘From our analysis of the 944 extremely long-lived [...]

april 11th, 2018|

Scientific Conference – Longitudinal Studies – Genome Campus Hinxton

30 May-1 June 2018 - Wellcome Genome Campus, Hinxton, UK Longitudinal studies are ideal tools for studying age-related functional changes, and the development and progression of chronic diseases. This conference will bring together scientists working on studies in childhood, adult and late life to identify novel biomarkers of functional decline and development of disease susceptibility, and to understand the lifetime drivers and underlying pathways of these processes. The programme will showcase new findings, methods [...]

maart 14th, 2018|

News from the board – Public Private Partnership (PPPs)

One of the activities for 2018 that DuSRA is trying to launch,  is to set up a public private partnership in the field of ageing. The board submitted an initial concept to ZonMW to get the oppurtunity to be selected in the proposition of ZonMW and the Topsectors. The initiative called VOILA: Vitality Oriented Innovations for the Lifecourse of the Ageing Society, has indeed been chosen for further development. At the moment we are working [...]

maart 13th, 2018|

 Postdoctoral Positions in Human Functional Genomics of Aging and Disease – Albert Einstein College of Medicine

The Suh Laboratory at the Albert Einstein College of Medicine is actively seeking 3-4 highly motivated postdoctoral fellows interested in any of the following areas: (1) Genetics of Human Aging-Related Disease including Alzheimer’s Disease. (2) Genome Maintenance/Cellular Senescence in Aging and Disease. (3) Computational and Bioinformatics Approaches to Human Aging and Disease. Research focus: The Sub lab is interested in understanding genetic and molecular mechanisms that underlie the interface of intrinsic aging and disease [...]

maart 13th, 2018|

The Famine Ended 70 Years Ago, but Dutch Genes Still Bear Scars

By Carl Zimmer Jan. 31, 2018 In September 1944, trains in the Netherlands ground to a halt. Dutch railway workers were hoping that a strike could stop the transport of Nazi troops, helping the advancing Allied forces. But the Allied campaign failed, and the Nazis punished the Netherlands by blocking food supplies, plunging much of the country into famine. By the time the Netherlands was liberated in May 1945, more than 20,000 people had [...]

februari 5th, 2018|

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

Science Advances | 03-01-2018 Abstract Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies remains scarce. Therefore, we evaluated whether DNAm in whole blood mediated the association between prenatal famine exposure and metabolic health in 422 individuals exposed to famine in utero and 463 (sibling) controls. We implemented a two-step analysis, namely, a genome-wide [...]

februari 5th, 2018|

2nd International Health & Wealth Conference (IHW 2018)

28-30 October 2018 | Penang Island, Malaysia Health meets Wealth live - IHW is getting shape for Penang “Health meets Wealth” to debate one of the world´s most prosperous and developing cross-section markets of modern community. The 2nd International Health & Wealth Conference (IHW 2018) is unique – a networking event which gathers decision makers, researchers and leading industry professionals to share market intelligence and thought leadership. International experts from 5 continents discuss future [...]

januari 29th, 2018|

A p300 and SIRT1 Regulated Acetylation Switch of C/EBPa Controls Mitochondrial Function

Cell Press  | 9 januari 2018 | Summary Cellular metabolism is a tightly controlled process in which the cell adapts fluxes through metabolic  pathways in response to changes in nutrient supply. Among the transcription factors that regulate  gene expression and thereby cause changes in cellular metabolism is the basic leucine-zipper (bZIP) transcription factor CCAAT/enhancer-binding protein alpha (C/EBPa). Protein lysine acetylation is a key post-translational modification (PTM) that integrates cellular metabolic cues with other  physiological [...]

januari 22nd, 2018|

European Human Genetics Conference 2018

Milan, Italy  | June 16-19 2018 European Human Genetics Conference 2018 joint with the European Meeting on Psychosocial Aspects of Genetics 2018 Dear Colleagues, The Scientific Programme Committee has again endeavoured to set up an exciting programme at the cutting-edge of current human genetics research. The programme includes 4 Plenary Sessions, 19 Invited Symposia, 24 Concurrent Sessions from submitted abstracts, 18 Workshops, 16 Educational Sessions (more education-focused, broader-view-type of sessions), Poster Sessions with ample viewing [...]

januari 9th, 2018|