Nieuws 2018-01-08T13:15:02+00:00


The Famine Ended 70 Years Ago, but Dutch Genes Still Bear Scars

By Carl Zimmer Jan. 31, 2018 In September 1944, trains in the Netherlands ground to a halt. Dutch railway workers were hoping that a strike could stop the transport of Nazi troops, helping the advancing Allied forces. But the Allied campaign failed, and the Nazis punished the Netherlands by blocking food supplies, plunging much of the country into famine. By the time the Netherlands was liberated in May 1945, more than 20,000 people had [...]

februari 5th, 2018|

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

Science Advances | 03-01-2018 Abstract Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies remains scarce. Therefore, we evaluated whether DNAm in whole blood mediated the association between prenatal famine exposure and metabolic health in 422 individuals exposed to famine in utero and 463 (sibling) controls. We implemented a two-step analysis, namely, a genome-wide [...]

februari 5th, 2018|

2nd International Health & Wealth Conference (IHW 2018)

28-30 October 2018 | Penang Island, Malaysia Health meets Wealth live - IHW is getting shape for Penang “Health meets Wealth” to debate one of the world´s most prosperous and developing cross-section markets of modern community. The 2nd International Health & Wealth Conference (IHW 2018) is unique – a networking event which gathers decision makers, researchers and leading industry professionals to share market intelligence and thought leadership. International experts from 5 continents discuss future [...]

januari 29th, 2018|

A p300 and SIRT1 Regulated Acetylation Switch of C/EBPa Controls Mitochondrial Function

Cell Press  | 9 januari 2018 | Summary Cellular metabolism is a tightly controlled process in which the cell adapts fluxes through metabolic  pathways in response to changes in nutrient supply. Among the transcription factors that regulate  gene expression and thereby cause changes in cellular metabolism is the basic leucine-zipper (bZIP) transcription factor CCAAT/enhancer-binding protein alpha (C/EBPa). Protein lysine acetylation is a key post-translational modification (PTM) that integrates cellular metabolic cues with other  physiological [...]

januari 22nd, 2018|

European Human Genetics Conference 2018

Milan, Italy  | June 16-19 2018 European Human Genetics Conference 2018 joint with the European Meeting on Psychosocial Aspects of Genetics 2018 Dear Colleagues, The Scientific Programme Committee has again endeavoured to set up an exciting programme at the cutting-edge of current human genetics research. The programme includes 4 Plenary Sessions, 19 Invited Symposia, 24 Concurrent Sessions from submitted abstracts, 18 Workshops, 16 Educational Sessions (more education-focused, broader-view-type of sessions), Poster Sessions with ample viewing [...]

januari 9th, 2018|

1e Nationaal Ouderen en Voeding Congres

Ede (GLD) - 7 maart 2018 Om langer te leven en om chronische ziekten en beperkingen zo lang mogelijk uit te stellen, is gezonde voeding en voldoende lichaamsbeweging belangrijk. Dit geldt ook voor ouderen met dementie. Echter, zijn er nog veel onduidelijkheden over de wetenschappelijke onderbouwing, de diagnostiek en behandeling van voedingsproblemen bij ouderen. ​Welke specifieke voedingsstoffen zijn van belang voor ouderen met dementie? Hoe kan je ondervoeding herkennen en voorkomen? Welke interacties zijn er tussen voeding en geneesmiddelen? Wat is de [...]

januari 9th, 2018|

Healthy Ageing: From Molecules to Organisms

Hixton, UK, 31 January - 2 February 2018 The registration deadline is approaching for Healthy Ageing. The meeting will focus on recent discoveries and current challenges in ageing research, including translating basic research insights into health improvement for older people. View the draft programme. The conference will explore how recent developments in cell- and immune-senescence, neuroinflamation, stem cells and epigenetics are leading to an increased understating of the ageing process. There will [...]

december 14th, 2017|

Ageing Meeting: a successful second edition!

Molecular Biology of Ageing Meeting 2017 19 October 2017 ERIBA organised for the second time the Molecular Biology of Ageing Meeting, from the 8th to the 11th of October 2017 at the premises of UMCG. More than 200 participants from 64 different institutions worldwide attended the four-day Meeting. Andrew Dillin (Department of Molecular and Cell Biology at Berkeley) opened the event with a key note lecture on mitochondrial proteotoxic stress. Scientists that work on [...]

oktober 31st, 2017|

Dutch Cancer Society funds ageing research

August 22th 2017 The Dutch Cancer Society has awarded funding for the Calkhoven and Demaria labs in ERIBA. The Calkhoven team (http://eriba.umcg.nl/groups/gene-regulation-in-ageing-and-age-related-diseases/) will use this funding to investigate the role of mitochondria in the maintenance of cancers that are driven by the oncogene MYC, aiming to identify novel therapeutic strategies. The Demaria team (http://eriba.umcg.nl/groups/cellular-senescence-and-age-related-pathologies/) will study the role of cellular senescence during melanoma and focus on how senescent cells generated by ultra-violet radiation affect melanoma progression [...]

september 5th, 2017|

Postgraduate Course – Epigenesis & Epigenetics –

Physiological consequences of perinatal nutritional programming May 31 - June 2 2017 - Wageningen Conditions during development and early life may have profound effects on physiological functioning and phenotypes and health in later life. This course aims to provide a detailed scientific background on the epigenetic mechanisms that mediate the link between development and adult phenotypes, both at the physiological and gene expression level. The program contains state-of-the-art lectures on epigenetic mechanisms, their [...]

maart 20th, 2017|